Paleoviruses, Viral infections and Viral Replication

Paleovirology is the term used to describe the study of viruses which cannot leave behind physical fossils. Virion structural protein derived from the amino-terminal domain of the Gag polyprotein. Phylogenetic analysis of Endogenous Viral Elements (EVEs) across multiple host species exhibit novel information about the evolution of diverse virus groups. EVEs have been adopted as inhibitors of viral infection.Viral infection occurs when an organism's body is invaded by pathogenic viruses, and virions attach to and enter susceptible cells. Viral infection is usually detected by clinical monitoring, for instance severe muscle and joint pains preceding fever, skin rash. Viruses are Intracellular obligate parasites that they cannot replicate their genes without the help of a living cell. Certain proteins on the virus particle must fit particular receptor sites on the particular host cell surface. Host cell provides the energy & system for the synthesis of viral proteins & nucleic acids. 

  • Physical fossils
  • Endogenous retroviruses
  • DNA viruses and RNA genome
  • Non-retroviral Integrated RNA Virus
  • Germline cells
  • mRNA synthesis and RNA replicase enzymes
  • viral protein synthesis

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